未知题型 【简答题】case study A 25-year-old Mediterranean female presents to her obstetrician at 12-weeks gestation for her first prenatal visit. This is her first pregnancy, and she is concerned about her baby and the risk of inheriting a “blood ” disease like others in her family. The patient reports a personal history of mild anemia but nothing as severe as her brother who required frequent transfusions and died at age 10. The patient was told by her physician that she did not need to take iron supplementation for her anemia. Patient deny having any anemic symptoms. Her physical exam is consistent with a 12-week pregnancy and ultrasound confirmed an intrauterine pregnancy at 12-weeks gestation. The patient’s hemoglobin level shows a hypochromic, microcytic( small sized red cell) anemia( hemoglobin, 9g/dL) and hemoglobin electrophoresis demonstrated increased hemoglobin A2 level( 4.0 percent) and increased fetal hemoglobin level, a pattern consistent with β thalassemia minor. The patient underwent chorionic villus sampling to assess whether the fetus was affected, and the diagnosis returned in several hours. What is the molecular genetics behind this disorder? What was the likely test and what is the biochemical basis?

未知题型 （ ）、（ ）是串口的4种工作方式选择位。

判断题 在保持矩形截面梁横截面面积不变的前提下，增大截面的高度能够提高梁抗横向剪切的强度